Louis Sareno, um jovem nascido na máfia, está procurando uma saída para a única vida que ele já conheceu.

After a toxic spill creates an infectious outbreak, causing people to be filled with rage and turning to cannibalism, four survivors converge upon a house nestled deep in the woods. Together, they must try to survive the madness happening outside, the uncertainty and each other. As things become more grim, hope fades and supplies run low, people's true selves begin to show. The four must try to survive the monsters outside and within.